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Dr Tso

細菌怕怕

一月底,成報披登了一篇我的專訪,題目是﹕「香港鍾馗﹕不得搞鬼」(仍掛在我網站的「傳媒看我」欄,大家歡迎瀏覽)。過獎過獎,豈敢豈敢;我至少有兩個魔鬼未拿住,敕令開壇﹗中山先生說過﹕「革命尚未城功,同志仍需努力﹗」。魔鬼作惡,此刻猶烈﹗其一是殖民地奴才的心魔復活,其次是瘟雞的陰魂不散。急急如律令,應斬即斬,不在話下。

且說人怕魔鬼、病毒與惡菌,你我雖有不同說法,其敬而遠之的心態一也。那麼,細菌怕不怕人﹖我是老牌權威,可以發言。

要研究細菌怕不怕人,並非容易,你以無限威嚴,粗手粗腳,一下子用高溫、消毒藥和抗生素把細菌打落十八重地獄,仍不知牠怕不怕你,因為死無對證;活口消滅了,反而成為懸案,對研究不利。

我 們可問﹕如果我們把一把降魔劍放在細菌身邊,牠眼尾瞥見了,拔腿便跑,走直了辮尾,這還不是細菌怕劍與怕弄劍的人的証據嗎﹖這把劍,只需擺放、並無舞弄, 說不上對細菌逼供,合乎「菌」道,而菌兒還不免要一走,不就露出細菌的心態嗎﹖細菌怕怕,自然就會逃之夭夭。當然,上面的說法是大大地簡化了實驗的難度。 我作為第一個研究這問題的人,初遇問題時真像老鼠拉龜、沒處落手﹗細菌這麼小,牠喜惡一件事物又不會告訴你;要是有所逃避的,太小了,又是成堆成群的,你 怎測定牠避不避難呢﹗然而,我扎職「細菌鍾馗」就由這開步始。

我的博士論文就攻這個關,研究大腸桿菌的「負」趨化性(negative chemotaxis), 看細菌有無所怕、怕甚麼、怎怕法和怕有甚麼生理效益。我們萬物之靈的人類有五官,大家可能沒注意到,原來原始的物種如細菌也有感官,這些感官,細如受體蛋 白,但卻可以提點細菌何所喜、何所怕,而且,當憂喜參半時,細菌還可以像我們用腦子般做抉擇,知所選取。這話今日說出來倒輕鬆,今日我們固然可以用專功能 的免疫蛋白把細菌的鞭毛黏住,讓牠在顯微鏡下打轉,由動的旋律譯成訊號、也可用電腦三維空間的變位參數解讀細菌這個「怕怕」的心態;但在當日,我既不知細 菌怎叫怕、有沒有怕這回事和用甚麼作降魔劍叫牠怕怕呢﹖在全不知情之下,盲人非洲黑夜捉烏鴉﹗怎去設計測試的實驗呢﹖……可幸就靠我鍾馗這套捉鬼的德行吧 ﹗

我 的探索很簡單;把一滴細菌放在玻片上,輕輕的把一條盛滿溶液的毛細管子擺貼菌滴的中心,過了一段時間,把游進毛細管細菌取出來,用微生物計量方法點算數 目、記下來。毛細管像條「逃生管道」,如果菌滴含有細菌怕怕的化合物,逃生管道不含,那麼細胞都「出自意願」地,走進逃生管道去避難。大家一看數据就可暸 如指掌。當然,實驗的具體細則涉及多重的對照,如果不謹慎細心,細菌不騙人、人也會受主觀騙。還好,我就靠這邏輯辯証,先發現了幾種細菌怕見的化合物,再 透過遺傳工程的手段,生化儀器檢定和化學分子模擬的方法,開始弄通細菌怕啥、怎怕和為甚麼怕。

大腸桿菌怕甚麼不重要,換了沙門氏菌,脾性大抵又有不同。值得珍惜的,恐怕還是那套科學的鍾馗手段﹕菌有多惡都不怕,摸通它的出沒規律,降魔劍掣起,它就只能乖乖就範﹗﹗

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Deprecated: Non-static method NSP_GK4_Utils::cutText() should not be called statically, assuming $this from incompatible context in /home/tsoww/www/www/tsow/modules/mod_news_pro_gk4/tmpl/layout.parts.php on line 200

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Deprecated: Non-static method NSP_GK4_Thumbs::getRealPath() should not be called statically, assuming $this from incompatible context in /home/tsoww/www/www/tsow/modules/mod_news_pro_gk4/gk_classes/gk.thumbs.php on line 32

Deprecated: Non-static method NSP_GK4_Thumbs::translateName() should not be called statically, assuming $this from incompatible context in /home/tsoww/www/www/tsow/modules/mod_news_pro_gk4/tmpl/layout.parts.php on line 306

Deprecated: Non-static method NSP_GK4_Thumbs::getRealPath() should not be called statically, assuming $this from incompatible context in /home/tsoww/www/www/tsow/modules/mod_news_pro_gk4/gk_classes/gk.thumbs.php on line 32

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毋離科學

保釣文獻編印與解讀

保釣文獻編印與解讀

11 五, 2009 | Hits:9898

五月的頭四天, 我夫婦倆赴新竹出席一個夢寐縈迴的保釣老鬼大聚舊。這個集會, 全名是「一九七○年代保釣運動文獻之編印與解讀」, Read more

毋離科學

「護老」「機械」、殷勤最解孤獨老「人」心

「護老」「機械」、殷勤最解孤獨老「人」心

04 五, 2009 | Hits:22093

有資深英文教師余姓讀者回應本欄四月廿日拙文「護老機器人」,我把來回兩份電郵意譯出來,供關心人士討論:- Read more

毋離科學

吾道不孤

吾道不孤

27 四月, 2009 | Hits:4668

             &n... Read more

毋離科學

護老機器人

護老機器人

20 四月, 2009 | Hits:4977

              這是個競科技... Read more

毋離科學

不准歧視無宗教!

不准歧視無宗教!

13 四月, 2009 | Hits:7674

上星期我以《有信何如做喇嘛!》為題寫了一文, 有人以為我立地成佛,信奉喇嘛。非也, Read more

毋離科學

有信何如做喇嘛!

06 四月, 2009 | Hits:2473

               正當「世界... Read more

毋離科學

世態「炎」「量」

02 五, 2003 | Hits:2105

第一個是SARS,Severeacute, respiratory syndrome,是此症登陸香港之時,某方面的人馬(總得透過英文的傳媒吧)把它「成功地」約定... Read more

毋離科學

科學殲疫建新功

25 四月, 2003 | Hits:2075

內地抗炎,最近出現了峰迴路轉的情景,如果單看病號的數字 計算,其中通報機制這關,不能說不出現了問題,前後兩天,帶病者倍增,究竟是記帳混亂還是有意隱瞞呢﹖此其一;... Read more

毋離科學

國內遏疫:行與不行

18 四月, 2003 | Hits:5113

在這場「非典型肺炎」的「遏疫」戰中,中國的戰場,有 「行」有「不行」。行與不行會﹖時轉化;掌握得好,可變成為個都是「行」,也非奢望;而且這個「現場」比較,是個小... Read more

毋離科學

誰的病?

11 四月, 2003 | Hits:2356

對於禍從天降的「非典型肺炎」我托賴還未發病,所以我是旁觀者﹗至於明天的我會不會發病,是另一回事,我這一個有愛惜心的旁觀者,既不怕病、也不惹病,為己為人,做足應做... Read more

毋離科學

「後疫期」怎打算?

04 四月, 2003 | Hits:3736

今日談疫症、SARS疫症,我以為最值得注意的己經不是怎防怎醫的問題,而是「後疫期香港經濟」的問題。話出有因:這個疫症在世界疫症史上來說,只是銀樣臘槍頭,多少仍是... Read more

毋離科學

給「心」「肺」戰士

28 三月, 2003 | Hits:4052

當今我們面臨兩場仗﹕一場在遠、一場在近;遠的屬心戰,是良心之戰,近的是肺戰,是肺炎之戰,都是肌體大戰,大家都得小心應付。 先 講肺戰,香港今年不幸,首遇變臉病... Read more

毋離科學

世上的水﹗

21 三月, 2003 | Hits:2093

我這個終生讀書人,由小學到博士學位的五個求學的建制階段中,有三個階段和耶穌打過交道,雖然其間瑪利亞的角色也曾忽隱忽現過,但總的來說,天主基督兩教,還是離不開以耶... Read more

毋離科學

我透你明

我透你明

07 三月, 2003 | Hits:17537

香港人此時的心態是聞雞瘟而色變,H5病毒不知何時來,來了便令一類人驚、一類人手忙腳亂,另一類人大造文章。指桑罵槐。所有的雞隻﹕老雞、嫩雞、童子雞,只要嗚眉瞌睡的... Read more

毋離科學

細菌怕怕

28 二月, 2003 | Hits:2611

一月底,成報披登了一篇我的專訪,題目是﹕「香港鍾馗﹕不得搞鬼」(仍掛在我網站的「傳媒看我」欄,大家歡迎瀏覽)。過獎過獎,豈敢豈敢;我至少有兩個魔鬼未拿住,敕令開... Read more

毋離科學

要好奇!

21 二月, 2003 | Hits:16348

四大發明像四枝火把、把中國科學事業的成就照得光亮亮,這火把的光芒不單照遍大地,沒有它,今日執牛耳的西方科技萌芽與文明開拓的序幕,也恐怕大大地延期拉開﹗甚而至之,... Read more